49ers Injury Report: Gross-Matos, Bethune, Okuayinonu OUT vs. Titans | #TENvsSF Preview (2026)

Bold headline: Five Titans inactivity shadows a crucial late-season showdown with the 49ers. But here’s where it gets controversial: injuries and lineup shifts could redefine this late-December clash.

The San Francisco 49ers are back from their Week 14 bye and ready to host the Tennessee Titans on their home turf. Head coach Kyle Shanahan reflected on the unusual timing of the bye, noting it felt different to have a late-season break. He described it as a peaceful pause after a grueling stretch and said the team is eager for the most important segment of the year in football—the playoffs and the stretch run.

That extra rest is particularly meaningful for players nursing injuries. Fullback Kyle Juszczyk, who suffered a rib fracture in the Week 13 win over Cleveland, was limited in practices midweek but practiced fully on Friday, signaling a positive trajectory toward returning. Kicker Eddy Piñeiro, who earned the NFC Special Teams Player of the Month for October, also logged full participation in all three practices for the first time since Week 11 as he works his way back from a hamstring issue.

For the Titans game, the 49ers have five players listed as OUT. This creates attention on how the depth chart will respond in a pivotal late-season matchup.

These developments matter not just for this game but for the broader playoff picture. If Juszczyk and Piñeiro are further eased into action, the 49ers could gain valuable contributions from their specialists and fullback as they push toward their postseason goals. On the Titans side, evaluating who steps up in the absence of key players could shape how San Francisco approaches game planning and in-game adjustments.

Question for readers: Do you think the 49ers’ late-season rest will translate into a sharper finish, or will the absence of five players against a competitive Titans squad neutralize that advantage? Share your thoughts in the comments.

49ers Injury Report: Gross-Matos, Bethune, Okuayinonu OUT vs. Titans | #TENvsSF Preview (2026)

References

Top Articles
Latest Posts
Recommended Articles
Article information

Author: Corie Satterfield

Last Updated:

Views: 6363

Rating: 4.1 / 5 (42 voted)

Reviews: 81% of readers found this page helpful

Author information

Name: Corie Satterfield

Birthday: 1992-08-19

Address: 850 Benjamin Bridge, Dickinsonchester, CO 68572-0542

Phone: +26813599986666

Job: Sales Manager

Hobby: Table tennis, Soapmaking, Flower arranging, amateur radio, Rock climbing, scrapbook, Horseback riding

Introduction: My name is Corie Satterfield, I am a fancy, perfect, spotless, quaint, fantastic, funny, lucky person who loves writing and wants to share my knowledge and understanding with you.